Cynthia Hawkins Selected Research

Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)

11/2015	Poly-ADP-Ribose Polymerase as a Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma and Pediatric High-Grade Astrocytoma.
3/2010	Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets.

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Cynthia Hawkins Research Topics

Disease

95	Neoplasms (Cancer) 05/2022 - 01/2003
28	Glioma (Gliomas) 01/2022 - 09/2009
21	Diffuse Intrinsic Pontine Glioma 01/2022 - 03/2010
19	Medulloblastoma 01/2022 - 09/2004
13	Brain Neoplasms (Brain Tumor) 10/2020 - 02/2006
12	Astrocytoma (Pilocytic Astrocytoma) 01/2018 - 01/2003
11	Ependymoma 01/2020 - 04/2006
10	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 02/2011
4	Brain Stem Neoplasms (Brain Stem Tumor) 01/2022 - 03/2010
4	Carcinogenesis 01/2022 - 01/2017
4	Carcinoma (Carcinomatosis) 12/2020 - 01/2003
4	Disease Progression 01/2019 - 04/2008
3	Choroid Plexus Papilloma 01/2019 - 04/2010
3	Sarcoma (Soft Tissue Sarcoma) 11/2017 - 12/2003
3	Neoplasm Metastasis (Metastasis) 01/2016 - 09/2004
2	Central Nervous System Neoplasms 02/2020 - 09/2009
2	Choroid Plexus Neoplasms (Choroid Plexus Tumor) 01/2019 - 01/2015
2	Hemorrhage 04/2016 - 05/2015
2	Muscle Hypotonia (Hypotonia) 04/2016 - 05/2012
2	Hypoxia (Hypoxemia) 01/2016 - 02/2011
2	Muscular Dystrophies (Muscular Dystrophy) 05/2012 - 02/2006
1	Nervous System Neoplasms (Neoplasms, Nervous System) 01/2022
1	Rhabdomyosarcoma 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Cysts 01/2021
1	Li-Fraumeni Syndrome 01/2020
1	Multiple Hamartoma Syndrome (Cowden's Disease) 01/2020
1	Pinealoma (Pineoblastoma) 01/2020
1	Turcot syndrome 01/2020
1	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2020

Drug/Important Bio-Agent (IBA)

24	dipinacoline glutamateIBA 01/2022 - 03/2010
15	Proteins (Proteins, Gene)FDA Link 05/2022 - 01/2003
15	Biological ProductsIBA 01/2021 - 09/2004
12	Histones (Histone)IBA 12/2020 - 09/2012
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2013
6	Phosphotransferases (Kinase)IBA 01/2020 - 09/2004
5	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2014
5	Mitogen-Activated Protein KinasesIBA 12/2020 - 01/2017
4	RNA (Ribonucleic Acid)IBA 02/2020 - 02/2012
4	DNA (Deoxyribonucleic Acid)IBA 11/2016 - 01/2012
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 01/2018
3	Lysine (L-Lysine)FDA Link 12/2020 - 03/2013
3	ChromatinIBA 10/2020 - 01/2017
3	EnzymesIBA 01/2020 - 02/2006
3	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2019 - 04/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2016 - 05/2007
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 05/2015 - 03/2010
3	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2014 - 02/2006
3	Messenger RNA (mRNA)IBA 11/2013 - 07/2011
3	Glial Fibrillary Acidic ProteinIBA 05/2007 - 01/2003
2	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2019
2	ErbB Receptors (EGF Receptor)IBA 01/2022 - 05/2015
2	AZD 6244IBA 01/2022 - 01/2018
2	AntigensIBA 02/2020 - 04/2008
2	Sirolimus (Rapamycin)FDA Link 01/2020 - 09/2015
2	6-chloro-2-(1-piperazinyl)pyrazine (CPP)IBA 01/2019 - 01/2015
2	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2019 - 01/2015
2	tyrosine receptor (receptor, tyrosine)IBA 01/2019 - 05/2008
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 11/2017 - 03/2015
2	NucleotidesIBA 07/2017 - 03/2009
2	Indicators and Reagents (Reagents)IBA 11/2016 - 01/2014
2	Temozolomide (Temodar)FDA LinkGeneric 03/2016 - 01/2012
2	Coloring Agents (Dyes)IBA 03/2016 - 06/2015
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2016 - 08/2015
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2015 - 03/2010
2	HexokinaseIBA 08/2015 - 02/2011
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 05/2015 - 09/2004
2	ParaffinIBA 11/2013 - 04/2012
2	Formaldehyde (Formol)FDA Link 11/2013 - 04/2012
2	Transcription Factors (Transcription Factor)IBA 05/2013 - 06/2011
2	Creatine Kinase (Creatine Phosphokinase)IBA 05/2012 - 03/2009
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 04/2006 - 09/2004
1	CannabidiolIBA 05/2022
1	human ERBB2 proteinIBA 01/2022
1	Tuberculin (PPD)IBA 01/2022
1	Neurofibromin 1 (Neurofibromin)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Circular RNAIBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 11/2020
1	Glucose (Dextrose)FDA LinkGeneric 11/2020
1	Mitochondrial DNA (mtDNA)IBA 11/2020
1	Polycomb Repressive Complex 1IBA 10/2020
1	Benzoates (Benzoate)IBA 01/2020
1	Azacitidine (5 Azacytidine)FDA Link 01/2020
1	Glycine Hydroxymethyltransferase (Serine Hydroxymethyltransferase)IBA 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2020
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2020
1	Glutamate DehydrogenaseIBA 01/2020
1	5,6,7,8-tetrahydrofolic acid (tetrahydrofolate)IBA 01/2020
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2020
1	ProteomeIBA 01/2020
1	Serine (L-Serine)FDA Link 01/2020

Therapy/Procedure

40	Therapeutics 01/2022 - 12/2003
19	Drug Therapy (Chemotherapy) 01/2021 - 07/2004
14	Radiotherapy 01/2022 - 07/2004
4	Re-Irradiation 10/2019 - 01/2018
3	Craniotomy 01/2021 - 07/2004
2	Immunotherapy 01/2022 - 11/2021
2	Precision Medicine 01/2022 - 01/2022
2	Craniospinal Irradiation 01/2019 - 12/2016